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LKC Technologies utas-2000
Utas 2000, supplied by LKC Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/utas+2000+system/erg+test+system+utas+2000/pm38896924-243-37-38
Average 90 stars, based on 1 article reviews
utas-2000 - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Prevalence of Rhodopsin mutations in autosomal dominant Retinitis Pigmentosa in Spain: clinical and analytical review in 200 families.
Article Snippet: Purpose: We aimed to determine the prevalence of mutations in the RHO gene in Spanish families with autosomal dominant Retinitis Pigmentosa (adRP), to assess genotype–phenotype correlations and to establish an accurate diagnostic algorithm after 23 years of data collection.. Patients and Methods: Two hundred patients were analysed through a combination of denaturing gradient gel electrophoresis, single-strand conformation polymorphism, genotyping microarray and Sanger sequencing of the RHO gene.. Results: Overall, 42 of 200 Spanish adRP families were mutated for RHO (21.0%).

Article Title: Molecular modeling of retinoschisin with functional analysis of pathogenic mutations from human X-linked retinoschisis
Article Snippet: Full-field ERGs were recorded at NEI using a UTAS 2000 system (LKC Technologies, Gaithersburg, MD, USA) with Burian–Allen bipolar contact lens electrodes on each eye and a ground electrode on the forehead.

Article Title: A novel mutation of the RP1 gene (Lys778ter) associated with autosomal dominant retinitis pigmentosa
Article Snippet: 25 Scotopic and photopic Ganzfeld electroretinography was recorded according to the ISCEV standard 26 with an UTAS 2000 system (LKC Technologies, Gaithersburg, USA), and DTL electrodes.



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Toxicity profiles of PADI2 inhibitor. Evaluation of histology and function of retina after intravitreal injection of PBS and 2 µM BB-Cl-amidine in mice. (A) Visual acuity was evaluated through optomotor response in different groups. (B) The a-wave (left) and b-wave (right) were measured by <t>electroretinography</t> in different groups. (C and D) (C) Representative images (magnification, ×200) and (D) quantitative analyses of hematoxylin and eosin staining of various groups. (E and F) (E) Representative images (magnification, ×200) and (F) quantitative analyses of TUNEL assay. The number of apoptotic cells did not show a statistically significant difference between the groups. (G) Schematic of summary. Scale bar, 50 µm (n=3). Bars represent SEM. NS, not significant, as determined by unpaired Student's t-test.
Utas E 2000, supplied by LKC Technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Toxicity profiles of PADI2 inhibitor. Evaluation of histology and function of retina after intravitreal injection of PBS and 2 µM BB-Cl-amidine in mice. (A) Visual acuity was evaluated through optomotor response in different groups. (B) The a-wave (left) and b-wave (right) were measured by <t>electroretinography</t> in different groups. (C and D) (C) Representative images (magnification, ×200) and (D) quantitative analyses of hematoxylin and eosin staining of various groups. (E and F) (E) Representative images (magnification, ×200) and (F) quantitative analyses of TUNEL assay. The number of apoptotic cells did not show a statistically significant difference between the groups. (G) Schematic of summary. Scale bar, 50 µm (n=3). Bars represent SEM. NS, not significant, as determined by unpaired Student's t-test.
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Toxicity profiles of PADI2 inhibitor. Evaluation of histology and function of retina after intravitreal injection of PBS and 2 µM BB-Cl-amidine in mice. (A) Visual acuity was evaluated through optomotor response in different groups. (B) The a-wave (left) and b-wave (right) were measured by <t>electroretinography</t> in different groups. (C and D) (C) Representative images (magnification, ×200) and (D) quantitative analyses of hematoxylin and eosin staining of various groups. (E and F) (E) Representative images (magnification, ×200) and (F) quantitative analyses of TUNEL assay. The number of apoptotic cells did not show a statistically significant difference between the groups. (G) Schematic of summary. Scale bar, 50 µm (n=3). Bars represent SEM. NS, not significant, as determined by unpaired Student's t-test.
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Toxicity profiles of PADI2 inhibitor. Evaluation of histology and function of retina after intravitreal injection of PBS and 2 µM BB-Cl-amidine in mice. (A) Visual acuity was evaluated through optomotor response in different groups. (B) The a-wave (left) and b-wave (right) were measured by <t>electroretinography</t> in different groups. (C and D) (C) Representative images (magnification, ×200) and (D) quantitative analyses of hematoxylin and eosin staining of various groups. (E and F) (E) Representative images (magnification, ×200) and (F) quantitative analyses of TUNEL assay. The number of apoptotic cells did not show a statistically significant difference between the groups. (G) Schematic of summary. Scale bar, 50 µm (n=3). Bars represent SEM. NS, not significant, as determined by unpaired Student's t-test.
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Toxicity profiles of PADI2 inhibitor. Evaluation of histology and function of retina after intravitreal injection of PBS and 2 µM BB-Cl-amidine in mice. (A) Visual acuity was evaluated through optomotor response in different groups. (B) The a-wave (left) and b-wave (right) were measured by electroretinography in different groups. (C and D) (C) Representative images (magnification, ×200) and (D) quantitative analyses of hematoxylin and eosin staining of various groups. (E and F) (E) Representative images (magnification, ×200) and (F) quantitative analyses of TUNEL assay. The number of apoptotic cells did not show a statistically significant difference between the groups. (G) Schematic of summary. Scale bar, 50 µm (n=3). Bars represent SEM. NS, not significant, as determined by unpaired Student's t-test.

Journal: Oncology Reports

Article Title: Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice

doi: 10.3892/or.2023.8583

Figure Lengend Snippet: Toxicity profiles of PADI2 inhibitor. Evaluation of histology and function of retina after intravitreal injection of PBS and 2 µM BB-Cl-amidine in mice. (A) Visual acuity was evaluated through optomotor response in different groups. (B) The a-wave (left) and b-wave (right) were measured by electroretinography in different groups. (C and D) (C) Representative images (magnification, ×200) and (D) quantitative analyses of hematoxylin and eosin staining of various groups. (E and F) (E) Representative images (magnification, ×200) and (F) quantitative analyses of TUNEL assay. The number of apoptotic cells did not show a statistically significant difference between the groups. (G) Schematic of summary. Scale bar, 50 µm (n=3). Bars represent SEM. NS, not significant, as determined by unpaired Student's t-test.

Article Snippet: Optomotor response measurement (OptoMotry HD; CerebralMechanics) and electroretinography (cat. no. UTAS E-2000; LKC Technologies) were performed 1 week after injection according to previous guidelines ( ).

Techniques: Drug discovery, Injection, Staining, TUNEL Assay